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Ketamine Hydrochloride

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Ketamine is an anesthetic, a medication used for induction and maintenance of anesthesia. It is also used for acute pain management and treatment of depression. It induces dissociative anesthesia, a trance-like state providing pain reliefsedation, and amnesia

Ketamine HCL Liquid For Sale Near Me

ketamine hcl for sale. Ketamine hydrochloride is a nonbarbiturate anesthetic chemically designated dl 2-(0-chlorophenyl)-2- (methylamino) cyclohexanone hydrochloride. It is formulated as a slightly acid (pH 3.5-5.5) sterile solution for intravenous or intramuscular injection in concentrations containing the equivalent of either 10, 50 or 100 mg ketamine base per milliliter and contains not more than 0.1 mg/mL Phemerol® (benzethonium chloride) added as a preservative. The 10 mg/mL solution has been made isotonic with sodium chloride. ketamine hcl for sale online

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Ketamine hydrochloride injection is shown as the sole anesthetic operator for symptomatic and surgeries that don’t require skeletal muscle unwinding. buy Ketamine hydrochloride is most appropriate for short strategies; however, it tends to be utilized, with extra dosages, for longer methodology.

Ketamine hydrochloride injection for sale is shown for the acceptance of anesthesia preceding the organization of other general anesthetic agents. Ketamine hydrochloride injection is shown to enhance low-strength agents, for example, nitrous oxide. Barbiturates and ketamine hydrochloride, being artificially inconsistent due to accelerating arrangement, ought not to be injected from a similar syringe. buy ketamine hcl home delivery

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If the ketamine hydrochloride portion is expanded with diazepam, the two medications must be given independently. Try not to blend ketamine hydrochloride and diazepam in syringe or imbuement carafe. Due to quick enlistment following the underlying intravenous injection, the patient ought to be in an upheld position during the organization. buy ketamine hcl canada

The beginning of activity of ketamine hydrochloride is fast; an intravenous portion of 2 mg/kg (1 mg/lb) of body weight, for the most part, creates careful anesthesia inside 30 seconds after injection, with the anesthetic impact generally enduring five to ten minutes. If a more extended impact is wanted, extra augmentations can be managed intravenously or intramuscularly to keep up anesthesia without delivering significant combined effects. buy ketamine hcl usa

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DOSAGE AND ADMINISTRATION

Note: Barbiturates and ketamine hydrochloride, being chemically incompatible because of precipitate formation, should not be injected from the same syringe.

If the ketamine hydrochloride dose is augmented with diazepam, the two drugs must be given separately. Do not mix ketamine hydrochloride and diazepam in syringe or infusion flask. For additional information on the use of diazepam, refer to the WARNINGS and DOSAGE AND ADMINISTRATION Sections of the diazepam insert. buy ketamine hcl 

Drug Description

What is Ketamine Hydrochloride and how is it used?

Ketamine Hydrochloride is a prescription medicine used as a sedative for diagnostic and surgical procedures. Ketamine Hydrochloride may be used alone or with other medications.

Ketamine Hydrochloride belongs to a class of drugs called General Anesthetics, Systemic.

It is not known if Ketamine Hydrochloride is safe and effective in children younger than 16 years of age.

What are the possible side effects of Ketamine Hydrochloride?

Ketamine Hydrochloride may cause serious side effects including:

  • severe confusion,
  • hallucinations,
  • unusual thoughts,
  • extreme fear,
  • painful or difficult urination,
  • increased urination,
  • loss of bladder control,
  • blood in your urine,
  • lightheadedness,
  • slow heart rate,
  • weak or shallow breathing, and
  • jerky movements that may look like convulsions

Get medical help right away, if you have any of the symptoms listed above.

The most common side effects of Ketamine Hydrochloride include:

  • dream-like feeling,
  • blurred vision,
  • double vision,
  • dizziness,
  • drowsiness,
  • nausea,
  • vomiting,
  • loss of appetite, and
  • sleep problems (insomnia)

Tell the doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Ketamine Hydrochloride. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

DESCRIPTION

Ketamine hydrochloride is a nonbarbiturate anesthetic chemically designated dl 2-(0-chlorophenyl)-2- (methylamino) cyclohexanone hydrochloride. It is formulated as a slightly acid (pH 3.5-5.5) sterile solution for intravenous or intramuscular injection in concentrations containing the equivalent of either 10, 50 or 100 mg ketamine base per milliliter and contains not more than 0.1 mg/mL Phemerol® (benzethonium chloride) added as a preservative. The 10 mg/mL solution has been made isotonic with sodium chloride.

 

 

Ketamine Hydrochloride - Structural Formula Illustration

 

INDICATIONS

Ketamine hydrochloride injection is indicated as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. Ketamine hydrochloride is best suited for short procedures but it can be used, with additional doses, for longer procedures.

Ketamine hydrochloride injection is indicated for the induction of anesthesia prior to the administration of other general anesthetic agents.

Ketamine hydrochloride injection is indicated to supplement low-potency agents, such as nitrous oxide.

Specific areas of application are described in the CLINICAL PHARMACOLOGY Section.

DOSAGE AND ADMINISTRATION

Note: Barbiturates and ketamine hydrochloride, being chemically incompatible because of precipitate formation, should not be injected from the same syringe.

If the ketamine hydrochloride dose is augmented with diazepam, the two drugs must be given separately. Do not mix ketamine hydrochloride and diazepam in syringe or infusion flask. For additional information on the use of diazepam, refer to the WARNINGS and DOSAGE AND ADMINISTRATION Sections of the diazepam insert.

Preoperative Preparations

  1. While vomiting has been reported following ketamine hydrochloride administration, some airway protection may be afforded because of active laryngealpharyngeal reflexes. However, since aspiration may occur with ketamine hydrochloride and since protective reflexes may also be diminished by supplementary anesthetics and muscle relaxants, the possibility of aspiration must be considered. Ketamine hydrochloride is recommended for use in the patient whose stomach is not empty when, in the judgment of the practitioner, the benefits of the drug outweigh the possible risks.
  2. Atropinescopolamine, or another drying agent should be given at an appropriate interval prior to induction.

Onset And Duration

Because of rapid induction following the initial intravenous injection, the patient should be in a supported position during administration.

The onset of action of ketamine hydrochloride is rapid; an intravenous dose of 2 mg/kg (1 mg/lb) of body weight usually produces surgical anesthesia within 30 seconds after injection, with the anesthetic effect usually lasting five to ten minutes. If a longer effect is desired, additional increments can be administered intravenously or intramuscularly to maintain anesthesia without producing significant cumulative effects.

Intramuscular doses, in a range of 9 to 13 mg/kg (4 to 6 mg/lb) usually produce surgical anesthesia within 3 to 4 minutes following injection, with the anesthetic effect usually lasting 12 to 25 minutes.

The initial dose of ketamine hydrochloride administered intravenously may range from 1 mg/kg to 4.5 mg/kg (0.5 to 2 mg/lb). The average amount required to produce five to ten minutes of surgical anesthesia has been 2 mg/kg (1 mg/lb).

Note: The 100 mg/mL concentration of ketamine hydrochloride should not be injected intravenously without proper dilution. It is recommended the drug be diluted with an equal volume of either Sterile Water for injection, USP, Normal Saline, or 5% Dextrose in Water.

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